‘ Loop though the table  
For Each dr As DataRow In ds.Tables(0).Rows
     If (dr(“Name”) = “Mahesh” Then             
         dr.Delete()     
End If Next
ds.Tables(0).AcceptChanges()

ref: http://www.c-sharpcorner.com/UploadFile/mahesh/DeleteDataTableRows08242006123435PM/DeleteDataTableRows.aspx